Effects of anxiety and depression on medication adherence and quality of life in older adult hypertensive patients without clinical complications in county medical community

To explore the effects of anxiety and depression on medication compliance and quality of life in elderly hypertensive patients without clinical complications in county medical communities. A convenient sampling method was used to select 100 elderly hypertensive patients without clinical complications with and without anxiety and depression who visited the outpatient clinic of Jinjiang Hospital Medical Community from June 2019 to March 2021. They were divided into observation group and control group, respectively. The scores of Generalized Anxiety Questionnaire-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), Chinese version of Morisky Medication Adherence Scale (MMAS-8) and Short Form 36 (SF-36) were compared between the two groups, and Pearson correlation coefficient analysis and multivariate linear regression analysis were performed. The GAD-7 score (6.46±3.06) and PHQ-9 score (4.63±2.89) in the observation group were significantly higher than those in the control group (3.32±0.80, 2.28±1.31) (t =-9.94, -7.40, both P < 0.01). The MMAS-8 score (5.16±0.81) and SF-36 total score (59.99±8.48) in the observation group were significantly lower than those in the control group (6.21±0.46, 69.93±9.36) (t =11.28, 7.87, both P < 0.01). The GAD-7 score was negatively correlated with the MMAS-8 score and SF-36 total score (r =-0.64, -0.64, both P < 0.01), PHQ-9 score was significantly negatively correlated with MMAS-8 score and SF-36 total score (r =-0.60, -0.68, both P < 0.01), and MMAS-8 score was significantly positively correlated with SF-36 total score (r =0.77, P < 0.01). The coefficients of GAD-7 score and PHQ-9 score in the regression equation of MMAS-8 score were -0.190 and -0.190, respectively (R square =0.73, t =-16.65, -15.45, both P < 0.01), and the coefficients of GAD-7 score and PHQ-9 score in the regression equation of SF-36 total score were -2.256 and -2.631, respectively (R square =0.83, t =-20.55, -22.23, both P < 0.01). Anxiety and depression can reduce the medication compliance and quality of life of elderly hypertensive patients without clinical complications in county medical communities. They should be included in the hypertension management strategy of primary medical institutions for early identification and comprehensive intervention, which is innovative and scientific.